Cannabinoids and COVID-19
El Biali M.· Broers B. · Besson M. · Demeules J. https://doi.org/10.1159/000510799 Abstract Since the endocannabinoid system is involved in immune function, the effect of cannabinoid…
Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response
Long Chi Nguyen, Dongbo Yang, Vlad Nicolaescu, Thomas J. Best, Takashi Ohtsuki, Shao-Nong Chen, J. Brent Friesen, Nir Drayman, Adil Mohamed, Christopher Dann, Diane Silva, Haley Gula, Krysten A. Jones, J. Michael Millis, Bryan C. Dickinson, Savaş Tay, Scott A. Oakes, Guido F. Pauli, David O. Meltzer, Glenn Randall, Marsha Rich Rosner doi: https://doi.org/10.1101/2021.03.10.432967 ABSTRACT The rapid spread of COVID-19 underscores the…
Opportunities, Challenges and Pitfalls of Using Cannabidiol as an Adjuvant Drug in COVID-19
by Barbara Malinowska, Marta Baranowska-Kuczko , Aleksandra Kicman and Eberhard Schlicker Int. J. Mol. Sci.2021, 22(4),1986; https://doi.org/10.3390/ijms22041986 Received: 11 January 2021 / Revised: 11…
SARS-CoV2 induced respiratory distress: Can cannabinoids be added to anti-viral therapies to reduce lung inflammation?
Figure: Potential mechanisms associated with cannabinoid mediated suppression of SARS-CoV-2 induced lung inflammation and fibrosis. ROS- Reactive oxygen species, IL-…
Cannabinoid Receptor Type 2: A Possible Target in SARS-CoV-2 (CoV-19) Infection?
Figure: Inflammatory response in lung after coronavirus (SARS-CoV-2) infection. Lung susceptibility to SARS-CoV-2 infection depends on viral spike proteins specificity…
Fighting the storm: could novel anti-TNFα and anti-IL-6 C. sativa cultivars tame cytokine storm in COVID-19?
Figure : Effects of novel C. sativa extracts on the levels of pro-inflammatory cytokines. To induce inflammation, human 3D EpiDermFT tissues were exposed to…
Immune Responses Regulated by Cannabidiol
Figure: Summary of CBD’s mechanisms of immune suppression. Overall, CBD’s immune system suppression is mediated by direct inhibition of various…
Cannabidiol (CBD) modulation of apelin in acute respiratory distress syndrome
Figure: CBD improved the symptoms of Poly(I:C)‐induced ARDS and normalized the expression level of apelin in the blood. Intranasal administration…
The potential of cannabidiol in the COVID-19 pandemic
Figure: The potential of cannabidiol (CBD) in SARS‐CoV2 infection. Cannadibidiol recognizes several receptor targets and displays a multifaceted immunomodulatory activity…
Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA
Figure: Anti-inflammatory effect of CBD after intranasal Poly(I:C) treatment. (A, B) Flow cytometry analysis showed that intranasal administration of Poly(I:C) effectuated lymphopenia and…